Since the completion of the Human Genome Project, single linear reference genomes (such as GRCh38) have served as the foundation for biomedical research. However, the genetic backgrounds of human ...

A research team led by Zhen-Xing Endowed Professor Jian Yang at the School of Life Sciences, Westlake University, has ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

A team of researchers has built a new protein sequencing workflow that pairs mirror proteases with deep learning software to ...

A federally funded study is coming to Minnesota to determine if whole genome sequencing at birth can reduce childhood ...