The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's ...

DNA replication begins with a set of proteins -- the Origin of Replication Complex (ORC). Researchers published images of the human ORC in exquisite detail, showing how it changes shapes in dramatic ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

In an ambitious collaboration, researchers added 1.8 million high-confidence protein complex structure predictions to the AlphaFold Database, accelerating molecular biology research.

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

A major advance in cell biology has revealed how our cells safeguard their genetic material during one of the most vulnerable moments in their life cycle. The study identifies a specific protein ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Proteins are among the most important molecular building blocks of life. They are chains of amino acids assembled in our cells by ribosomes, the molecular "protein factories" of our bodies. The ...